| Long name: |
ALEXA FLUOR 647 Conjugated, ATG3 (Tyr18) Polyclonal Antibody |
| Also known as: |
Anti-ATG3 Tyr18 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATG3 Tyr18 |
| Specificity: |
This is a highly specific antibody against ATG3 Tyr18 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr18 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ATG3 around the phosphorylation site of Tyr18 |
| Gene ID Number: |
64422 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy, ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3, Also acts as an autocatalytic E2-like enzyme, Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE), PE-conjugation to ATG8-like proteins is essential for autophagy, Preferred substrate is MAP1LC3A, catalyzing the conjugation of ATG12 to itself, E2-like enzyme involved in autophagy and mitochondrial homeostasis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PC3-96 FLJ22125 MGC15201 DKFZp564M1178 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ATG3 (Tyr18) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ATG3 (Tyr18) |
| Short name: |
ATG3 (Tyr18) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, autophagy related 3 (Tyr18) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATG3 and IDBG-49891 and ENSG00000144848 and 64422, ATG3 and IDBG-632300 and ENSBTAG00000009084 and 508571, Atg3 and IDBG-162821 and ENSMUSG00000022663 and 67841, Cytoplasm, enzyme binding, this GO :0000045 and autophagic vacuole assembly and biological process this GO :0000153 and cytoplasmic ubiquitin ligase complex and cellular component this GO :0000422 and mitochondrion degradation and biological process this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006612 and protein targeting to membrane and biological process this GO :0006914 and autophagy and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0019776 and Atg8 ligase activity and molecular function this GO :0019777 and Atg12 ligase activity and molecular function this GO :0019787 and small conjugating protein ligase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0043653 and mitochondrial fragmentation involved in apoptotic process and biological process this GO :0044804 and nucleophagy and biological process this GO :1902017 and regulation of cilium assembly and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0019776 : Atg8 ligase activity and also this GO :0019777 : Atg12 ligase activity and also this GO :0019787 : small conjugating protein ligase activity and also this GO :0019899 : enzyme binding, this GO :0019776 : Atg8 ligase activity, this GO :0019777 : Atg12 ligase activity, this GO :0019787 : small conjugating protein ligase activity, this GO :0019899 : enzyme binding, autophagy related 3 |
| Identity: |
20962 |
| Gene: |
ATG3 |
More about : ATG3 |
| Long gene name: |
autophagy related 3 |
| Synonyms gene: |
APG3L |
| Synonyms gene name: |
APG3 autophagy 3-like (S, cerevisiae) , cerevisiae) ATG3 autophagy related 3 homolog (S |
| Locus: |
3q13, 2 |
| Discovery year: |
2004-07-05 |
| Entrez gene record: |
64422 |
| Pubmed identfication: |
11825910 |
| RefSeq identity: |
NM_022488 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000159260 |