| Long name: |
ATG3 (Tyr18) Primary Polyclonal Antibody |
| Also known as: |
ATG3 (Tyr18) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ATG3 Tyr18 |
| Specificity: |
This is a highly specific antibody against ATG3 Tyr18 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr18 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ATG3 around the phosphorylation site of Tyr18 |
| Gene ID number: |
64422 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy, ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3, Also acts as an autocatalytic E2-like enzyme, Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE), PE-conjugation to ATG8-like proteins is essential for autophagy, Preferred substrate is MAP1LC3A, catalyzing the conjugation of ATG12 to itself, E2-like enzyme involved in autophagy and mitochondrial homeostasis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APG3, APG3 autophagy 3 like, APG3 like, APG3-like, APG3L, ATG 3, ATG3, ATG3 autophagy related 3 homolog, ATG3 autophagy related 3 homolog S, ATG3_HUMAN, Apg 3, Apg3p, Autophagy Apg3p/Aut1p like, Autophagy related protein 3, Autophagy-related protein 3, DKFZp564M1178, FLJ22125, MGC15201, OTTHUMP00000214547, OTTHUMP00000214548, PC3 96, Protein PC3-96, Ubiquitin-like-conjugating enzyme ATG3, cerevisiae, hApg3, 2610016C12Rik |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATG3 (Tyr18) |
| Short name: |
ATG3 (Tyr18) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
autophagy related 3 (Tyr18) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATG3 and IDBG-49891 and ENSG00000144848 and 64422, ATG3 and IDBG-632300 and ENSBTAG00000009084 and 508571, Atg3 and IDBG-162821 and ENSMUSG00000022663 and 67841, Cytoplasm, enzyme binding, this GO :0000045 and autophagic vacuole assembly and biological process this GO :0000153 and cytoplasmic ubiquitin ligase complex and cellular component this GO :0000422 and mitochondrion degradation and biological process this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006612 and protein targeting to membrane and biological process this GO :0006914 and autophagy and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0019776 and Atg8 ligase activity and molecular function this GO :0019777 and Atg12 ligase activity and molecular function this GO :0019787 and small conjugating protein ligase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0043653 and mitochondrial fragmentation involved in apoptotic process and biological process this GO :0044804 and nucleophagy and biological process this GO :1902017 and regulation of cilium assembly and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0019776 : Atg8 ligase activity and also this GO :0019777 : Atg12 ligase activity and also this GO :0019787 : small conjugating protein ligase activity and also this GO :0019899 : enzyme binding, this GO :0019776 : Atg8 ligase activity, this GO :0019777 : Atg12 ligase activity, this GO :0019787 : small conjugating protein ligase activity, this GO :0019899 : enzyme binding, autophagy related 3 |
| Identity: |
20962 |
| Gene: |
ATG3 |
More about : ATG3 |
| Long gene name: |
autophagy related 3 |
| Synonyms gene: |
APG3L |
| Synonyms gene name: |
APG3 autophagy 3-like (S, cerevisiae) , cerevisiae) ATG3 autophagy related 3 homolog (S |
| Synonyms: |
PC3-96 FLJ22125 MGC15201 DKFZp564M1178 |
| Locus: |
3q13, 2 |
| Discovery year: |
2004-07-05 |
| Entrez gene record: |
64422 |
| Pubmed identfication: |
11825910 |
| RefSeq identity: |
NM_022488 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000159260 |