p53 (Phospho-Ser6) Antibody

Catalog number:	bs-50536R Buy Now
Price:	402 €
Supplier:	abebio
Product name:	p53 (Phospho-Ser6) Antibody
Quantity:	1x plate of 48 wells
Other quantities:	100ug 370€ 50ug 299€
Related search:	antibody isoform antigen tumor suppressor

More details Need more?:

Long name:	p53 (Phospho-Ser6) Primary Polyclonal Antibody
Also known as:	p53 (Phospho-Ser6) PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	p53 (Phospho-Ser6)
Specificity:	This is a highly specific antibody against p53 (Phospho-Ser6)
Modification(s):	Phosphorylation
Modification site(s):	Ser6
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Source:	Synthetic phospho-peptide
Gene ID number:	7157
Swiss Prot:	P04637
Tested Applications:	WB
Recommended dilutions:	000), WB (1:1
Cross reactivity:	Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, Implicated in Notch signaling cross-over, In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1, Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process, Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters, Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1, Isoform 7 inhibits isoform 1-mediated apoptosis, LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation, One of the activated genes is an inhibitor of cyclin-dependent kinases, Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2 (PubMed:24051492), induces growth arrest or apoptosis depending on the physiological circumstances and cell type, or by repression of Bcl-2 expression, the function is largely independent of transcription, thus stopping cell cycle progression, Acts as a tumor suppressor in many tumor types
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	Antigen NY-CO-13, BCC7, Cellular tumor antigen p53, LFS1, Phosphoprotein p53, TP53, TRP53, Tumor suppressor p53, P53
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	p53 (Phospho-Ser6)
Short name:	p53 (Phospho-Ser6) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	p53 (phosphorilated-Ser6) (Antibody to)
Alternative technique:	antibodies

• #antibody
• #isoform
• #antigen
• #tumor
• #suppressor