| Long name: |
ALEXA FLUOR 488 Conjugated, BAAT Polyclonal Antibody |
| Also known as: |
Anti-BAAT PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BAAT |
| Specificity: |
This is a highly specific antibody against BAAT |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
110-160/418 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BAAT |
| Gene ID Number: |
570 |
| Swiss Prot: |
Q14032 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In a first step the bile acids are converted to an acyl-CoA thioester, In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi, In turn, In vitro, May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids, May catalyze the conjugation of primary or secondary bile acids, The conjugation increases the detergent properties of bile acids in the intestine, The major components of bile are cholic acid and chenodeoxycholic acid, and conjugates glycine to these acyl-CoAs, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids), catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or both, or cytoplasmic at the endoplasmic reticulum (secondary bile acids), which facilitates lipid and fat-soluble vitamin absorption, Involved in bile acid metabolism |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
BAT |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the BAAT Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
BAAT |
| Short name: |
BAAT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, BAAT (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
932 |
| Gene: |
BAAT |
More about : BAAT |
| Long gene name: |
bile acid-CoA:amino acid N-acyltransferase |
| Synonyms gene name: |
bile acid Coenzyme A:amino acid N-acyltransferase (glycine N-choloyltransferase) bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) |
| Synonyms name: |
glycine N-choloyltransferase |
| Locus: |
9q31, 1 |
| Discovery year: |
1996-03-13 |
| GenBank acession: |
L34081 |
| Entrez gene record: |
570 |
| RefSeq identity: |
NM_001701 |
| Havana BLAST/BLAT: |
OTTHUMG00000020377 |