| Long name: |
FITC Conjugated, APOC3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APOC3 |
| Specificity: |
This is a highly specific antibody against APOC3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
55-100/101 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from rat Apolipoprotein CIII |
| Gene ID number: |
11814 |
| Swiss Prot: |
P33622 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Mouse |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors, Intracellularly, Plays a multifaceted role in triglyceride homeostasis, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs), extracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APOC3 Conjugated |
| Short name: |
FITC Conjugated, APOC3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, apolipoprotein C-III (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
APOC3 and IDBG-630792 and ENSBTAG00000012398 and 408009, APOC3 and IDBG-72562 and ENSG00000110245 and 345, APOCIII and HALP2, Apoc3 and IDBG-161220 and ENSMUSG00000032081 and 11814, Extracellular, high-density lipoprotein particle receptor binding, this GO :0001523 and retinoid metabolic process and biological process this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005769 and early endosome and cellular component this GO :0006641 and triglyceride metabolic process and biological process this GO :0006642 and triglyceride mobilization and biological process this GO :0006869 and lipid transport and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0007603 and phototransduction, this GO :0005543 : phospholipid binding, this GO :0005543 : phospholipid binding and also this GO :0008289 : lipid binding and also this GO :0015485 : cholesterol binding and also this GO :0030234 : enzyme regulator activity and also this GO :0055102 : lipase inhibitor activity and also this GO :0070653 : high-density lipoprotein particle receptor binding, this GO :0008289 : lipid binding, this GO :0015485 : cholesterol binding, this GO :0030234 : enzyme regulator activity, this GO :0055102 : lipase inhibitor activity, this GO :0070653 : high-density lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008289 and lipid binding and molecular function this GO :0010897 and negative regulation of triglyceride catabolic process and biological process this GO :0010903 and negative regulation of very-low-density lipoprotein particle remodeling and biological process this GO :0010916 and negative regulation of very-low-density lipoprotein particle clearance and biological process this GO :0010987 and negative regulation of high-density lipoprotein particle clearance and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0019433 and triglyceride catabolic process and biological process this GO :0030234 and enzyme regulator activity and molecular function this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034363 and intermediate-density lipoprotein particle and cellular component this GO :0034366 and spherical high-density lipoprotein particle and cellular component this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034379 and very-low-density lipoprotein particle assembly and biological process this GO :0034382 and chylomicron remnant clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042627 and chylomicron and cellular component this GO :0042632 and cholesterol homeostasis and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045717 and negative regulation of fatty acid biosynthetic process and biological process this GO :0045833 and negative regulation of lipid metabolic process and biological process this GO :0048261 and negative regulation of receptor-mediated endocytosis and biological process this GO :0050995 and negative regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055102 and lipase inhibitor activity and molecular function this GO :0060621 and negative regulation of cholesterol import and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process this GO :0070653 and high-density lipoprotein particle receptor binding and molecular function this GO :0071333 and cellular response to glucose stimulus and biological process, apolipoprotein C-III |
| Identity: |
610 |
| Gene: |
APOC3 |
More about : APOC3 |
| Long gene name: |
apolipoprotein C3 |
| Synonyms gene name: |
apolipoprotein C-III |
| Locus: |
11q23, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X01388 |
| Entrez gene record: |
345 |
| RefSeq identity: |
NM_000040 |
| Classification: |
Apolipoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000046115 |