| Long name: |
FITC Conjugated, ACOT8 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ACOT8 |
| Specificity: |
This is a highly specific antibody against ACOT8 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ACOT8 |
| Gene ID number: |
10005 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acyl-coenzyme A Thioesterase 8, It is a major thioesterase in peroxisomes and competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA), It shows a preference for medium-length fatty acyl-CoAs and may be involved in the metabolic regulation of peroxisome proliferation, also known as ACOT8 may mediate Nef-induced down-regulation of CD4, free fatty acids and CoASH, providing the potential to regulate intracellular levels of acyl-CoAs, Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
hACTE-III hTE PTE-2 NAP1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ACOT8 Conjugated |
| Short name: |
FITC Conjugated, ACOT8 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, ACOT8 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15919 |
| Gene: |
ACOT8 |
More about : ACOT8 |
| Long gene name: |
acyl-CoA thioesterase 8 |
| Synonyms gene: |
PTE1 |
| Synonyms gene name: |
peroxisomal acyl-CoA thioesterase peroxisomal acyl-CoA thioesterase 1 |
| Synonyms name: |
choloyl-CoA hydrolase Nef (lentivirus myristoylated factor) associated protein 1 |
| Locus: |
20q13, 12 |
| Discovery year: |
2001-08-01 |
| GenBank acession: |
AF014404 |
| Entrez gene record: |
10005 |
| Pubmed identfication: |
10092594 9153233 16103133 16940157 |
| RefSeq identity: |
NM_183386 |
| Classification: |
Acyl-CoA thioesterases |
| Havana BLAST/BLAT: |
OTTHUMG00000033045 |