| Long name: |
ACOT8 Primary Polyclonal Antibody |
| Also known as: |
ACOT8 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ACOT8 |
| Specificity: |
This is a highly specific antibody against ACOT8 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ACOT8 |
| Gene ID number: |
10005 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acyl-coenzyme A Thioesterase 8, It is a major thioesterase in peroxisomes and competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA), It shows a preference for medium-length fatty acyl-CoAs and may be involved in the metabolic regulation of peroxisome proliferation, also known as ACOT8 may mediate Nef-induced down-regulation of CD4, free fatty acids and CoASH, providing the potential to regulate intracellular levels of acyl-CoAs, Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ACOT8_HUMAN, Acot8, Acyl-CoA thioesterase 8, Acyl-coenzyme A thioesterase 8, Choloyl coenzyme A thioesterase, Choloyl-coenzyme A thioesterase, HIV Nef associated acyl CoA thioesterase, HIV-Nef-associated acyl-CoA thioesterase, HNAACTE, Long chain fatty acyl CoA hydrolase, PTE 1, PTE 2, PTE-1, PTE-2, PTE1, PTE2, Palmitoyl CoA hydrolase, Peroxisomal acyl CoA thioesterase 1, Peroxisomal acyl coenzyme A thioester hydrolase 1, Peroxisomal acyl-coenzyme A thioester hydrolase 1, Peroxisomal long chain acyl CoA thioesterase 1, Peroxisomal long-chain acyl-CoA thioesterase 1, Thioesterase II, acyl CoA thioesterase 8, hACTE III, hACTE-III, hACTEIII, hTE, ACTEIII |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ACOT8 |
| Short name: |
ACOT8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ACOT8 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15919 |
| Gene: |
ACOT8 |
More about : ACOT8 |
| Long gene name: |
acyl-CoA thioesterase 8 |
| Synonyms gene: |
PTE1 |
| Synonyms gene name: |
peroxisomal acyl-CoA thioesterase peroxisomal acyl-CoA thioesterase 1 |
| Synonyms: |
hACTE-III hTE PTE-2 NAP1 |
| Synonyms name: |
choloyl-CoA hydrolase Nef (lentivirus myristoylated factor) associated protein 1 |
| Locus: |
20q13, 12 |
| Discovery year: |
2001-08-01 |
| GenBank acession: |
AF014404 |
| Entrez gene record: |
10005 |
| Pubmed identfication: |
10092594 9153233 16103133 16940157 |
| RefSeq identity: |
NM_183386 |
| Classification: |
Acyl-CoA thioesterases |
| Havana BLAST/BLAT: |
OTTHUMG00000033045 |