| Long name: |
ALEXA FLUOR 488 Conjugated, NR2C2/TAK1 Polyclonal Antibody |
| Also known as: |
Anti-NR2C2/TAK1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NR2C2/TAK1 |
| Specificity: |
This is a highly specific antibody against NR2C2/TAK1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
490-540/596 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NR2C2/TAK1 |
| Gene ID Number: |
7182 |
| Swiss Prot: |
P49116 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activates transcriptional activity of LHCG, An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, Antagonist of PPARA-mediated transactivation, Appears to be important for neurodevelopmentally regulated behavior (By similarity), Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences, May regulate gene expression during the late phase of spermatogenesis, Plays a fundamental role in early embryonic development and embryonic stem cells, Required for normal spermatogenesis and cerebellum development, Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1, retinoid X, thyroid hormone receptor and estrogen receptor pathways, vitamin D3 receptor, Orphan nuclear receptor that can act as a repressor or activator of transcription |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
TAK1 TR2R1 hTAK1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the NR2C2/TAK1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
NR2C2/TAK1 |
| Short name: |
NR2C2/TAK1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, NR2C2/TAK1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7972 |
| Gene: |
NR2C2 |
More about : NR2C2 |
| Long gene name: |
nuclear receptor subfamily 2 group C member 2 |
| Synonyms gene: |
TR4 |
| Synonyms gene name: |
group C, member 2 , nuclear receptor subfamily 2 |
| Locus: |
3p25, 1 |
| Discovery year: |
1998-05-15 |
| GenBank acession: |
L27586 |
| Entrez gene record: |
7182 |
| Pubmed identfication: |
8661150 8016112 |
| RefSeq identity: |
NM_003298 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000129839 |