| Catalog number: | bs-4251R-Biotin |
|---|---|
| Price: | 456 € |
| Supplier: | fabgen |
| Product name: | PHD1 Antibody, Biotin Conjugated |
| Quantity: | 100 µg |
| Related search: |
| Long name: | Biotin Conjugated, PHD1 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | PHD1 |
| Specificity: | This is a highly specific antibody against PHD1 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human PHD1/prolyl hydroxylase |
| Gene ID number: | 112398 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | It functions as a cellular oxygen sensor and, It may play a role in cell growth regulation, and HIF-2 alpha, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex, under normoxic conditions, PHD1 catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins and hydroxylates HIF-1 alpha at Pro-402 and Pro-564 |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | PHD1 HIFPH1 |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | PHD1 Conjugated |
| Short name: | Conjugated, PHD1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, PHD1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 14660 |
| Gene: | EGLN2 | More about : EGLN2 |
| Long gene name: | egl-9 family hypoxia inducible factor 2 |
| Synonyms gene name: | egl nine homolog 2 (C, elegans) |
| Synonyms name: | HIF prolyl hydroxylase 1 |
| Locus: | 19q13, 2 |
| Discovery year: | 2001-08-21 |
| GenBank acession: | AJ310544 |
| Entrez gene record: | 112398 |
| Havana BLAST/BLAT: | OTTHUMG00000182703 |
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