Cullin 3 Antibody, Cy5 Conjugated

Catalog number:	bs-4211R-Cy5 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Cullin 3 Antibody, Cy5 Conjugated
Quantity:	0.1ml
Related search:	cullin antibody antibodies ubiquitination ligase pubmed the degradation

More details Need more?:

Long name:	Cy5 Conjugated, Cullin 3 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Cullin 3
Specificity:	This antibody may detect Cullin-4 A/B, This is a highly specific antibody against Cullin 3
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	430-480/768
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic peptide derived from human Cullin 3
Gene ID number:	8452
Swiss Prot:	Q13618
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme, BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, BCR(KLHL3) acts as a regulator of ion transport in the distal nephron, BCR(KLHL42) is involved in ubiquitination of KATNA1, BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis, BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL, GLI2 and GLI3, H2AFY and DAXX, PubMed:21670212, PubMed:21840486, PubMed:24768539), The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity), The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component, by mediating ubiquitination of WNK4, thereby playing a key role in collagen export, these complexes have lower ubiquitin ligase activity, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B), Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	625, 650nm/670nm
Synonyms:	CUL3, Cullin-3, KIAA0617, PHA2E, CUL-3
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Cullin 3 Conjugated
Short name:	Conjugated, Cullin 3 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy5
Alternative name:	cyanine 5 coupled, Cullin 3 (Antibody to)
Alternative technique:	antibodies

• #cullin
• #antibody
• #antibodies
• #ubiquitination
• #ligase
• #pubmed
• #the
• #degradation