| Long name: |
Cy5, 5 Conjugated, NF1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NF1 |
| Specificity: |
This is a highly specific antibody against NF1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Neurofibromin 1 |
| Gene ID number: |
4763 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alternatively spliced transcript variants encoding different isoforms have also been described for this gene, Jul 2008], Mutations in this gene have been linked to neurofibromatosis type 1, The mRNA for this gene is subject to RNA editing (CGA>, [provided by RefSeq, juvenile myelomonocytic leukemia and Watson syndrome, Arg1306Term) resulting in premature translation termination, This gene product appears to function as a negative regulator of the ras signal transduction pathway, UGA-> |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
NF1 Conjugated |
| Short name: |
Conjugated, NF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, neurofibromin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GABAergic and biological process this GO :0032318 and regulation of Ras GTPase activity and biological process this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0035021 and negative regulation of Rac protein signal transduction and biological process this GO :0042060 and wound healing and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042992 and negative regulation of transcription factor import into nucleus and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043473 and pigmentation and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0043535 and regulation of blood vessel endothelial cell migration and biological process this GO :0045124 and regulation of bone resorption and biological process this GO :0045671 and negative regulation of osteoclast differentiation and biological process this GO :0045685 and regulation of glial cell differentiation and biological process this GO :0045762 and positive regulation of adenylate cyclase activity and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0046580 and negative regulation of Ras protein signal transduction and biological process this GO :0046929 and negative regulation of neurotransmitter secretion and biological process this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048485 and sympathetic nervous system development and biological process this GO :0048593 and camera-type eye morphogenesis and biological process this GO :0048712 and negative regulation of astrocyte differentiation and biological process this GO :0048715 and negative regulation of oli this GO dendrocyte differentiation and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0048853 and forebrain morphogenesis and biological process this GO :0050890 and cognition and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, NF1 and IDBG-39462 and ENSG00000196712 and 102725369, NF1 and IDBG-631285 and ENSBTAG00000011829 and 280877, NFNS and VRNF and WSS, Nf1 and IDBG-203454 and ENSMUSG00000020716 and 18015, nuclei, phosphatidylcholine binding, this GO :0000165 and MAPK cascade and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001656 and metanephros development and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001889 and liver development and biological process this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001952 and regulation of cell-matrix adhesion and biological process this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0005096 and GTPase activator activity and molecular function this GO :0005099 and Ras GTPase activator activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007154 and cell communication and biological process this GO :0007165 and signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007406 and negative regulation of neuroblast proliferation and biological process this GO :0007420 and brain development and biological process this GO :0007422 and peripheral nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008429 and phosphatidylethanolamine binding and molecular function this GO :0008542 and visual learning and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0014044 and Schwann cell development and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0021510 and spinal cord development and biological process this GO :0021897 and forebrain astrocyte development and biological process this GO :0021915 and neural tube development and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0022011 and myelination in peripheral nervous system and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031210 and phosphatidylcholine binding and molecular function this GO :0031235 and intrinsic component of the cytoplasmic side of the plasma membrane and cellular component this GO :0032228 and regulation of synaptic transmission, this GO :0005096 : GTPase activator activity, this GO :0005096 : GTPase activator activity and also this GO :0005099 : Ras GTPase activator activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008429 : phosphatidylethanolamine binding and also this GO :0031210 : phosphatidylcholine binding, this GO :0005099 : Ras GTPase activator activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0008429 : phosphatidylethanolamine binding, this GO :0031210 : phosphatidylcholine binding, 4763, neurofibromin 1 |
| Identity: |
7765 |
| Gene: |
NF1 |
More about : NF1 |
| Long gene name: |
neurofibromin 1 |
| Synonyms name: |
neurofibromatosis von Recklinghausen disease Watson disease |
| Locus: |
17q11, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
4763 |
| Pubmed identfication: |
1715669 |
| RefSeq identity: |
NM_000267 |
| Havana BLAST/BLAT: |
OTTHUMG00000132871 |
| Locus Specific Databases: |
LOVD - Mendelian genes LRG_214 |