| Long name: |
ALEXA FLUOR 488 Conjugated, MAVS Polyclonal Antibody |
| Also known as: |
Anti-MAVS PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MAVS |
| Specificity: |
This is a highly specific antibody against MAVS |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAVS |
| Gene ID Number: |
5788 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Silencing of MAVS expression permits derepression of viral replication, while over expression of MAVS boosts antiviral immunity, MAVS (Mitochondrial Antiviral Signaling) mediates the activation of NF-kappaB and IRF3 in response to antiviral infection |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
VISA KIAA1271 IPS-1 Cardif |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MAVS Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
MAVS |
| Short name: |
MAVS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, mitochondrial antiviral signaling protein (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CARD domain binding, MAVS and IDBG-49080 and ENSG00000088888 and 57506, Mavs and IDBG-207066 and ENSMUSG00000037523 and 228607, Plasma membranes, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002218 and activation of innate immune response and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005778 and peroxisomal membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0033160 and positive regulation of protein import into nucleus, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0050700 : CARD domain binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0050700 : CARD domain binding, translocation and biological process this GO :0039529 and RIG-I signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0060340 and positive regulation of type I interferon-mediated signaling pathway and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process this GO :0071651 and positive regulation of chemokine (C-C motif) ligand 5 production and biological process this GO :0071660 and positive regulation of IP-10 production and biological process this GO :1900063 and regulation of peroxisome organization and biological process, 45349 and IDBG-640031 and ENSBTAG00000013545 and 618508, mitochondrial antiviral signaling protein |
| Identity: |
29233 |
| Gene: |
MAVS |
More about : MAVS |
| Long gene name: |
mitochondrial antiviral signaling protein |
| Synonyms name: |
virus-induced signaling adaptor IFN-B promoter stimulator 1 CARD adaptor inducing IFN-beta |
| Locus: |
20p13 |
| Discovery year: |
2009-04-01 |
| GenBank acession: |
DQ174270 |
| Entrez gene record: |
57506 |
| Pubmed identfication: |
16125763 16153868 |
| RefSeq identity: |
NM_020746 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031765 |