| Long name: |
ALEXA FLUOR 488 Conjugated, HK2/Hexokinase 2 Polyclonal Antibody |
| Also known as: |
Anti-HK2/Hexokinase 2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HK2/Hexokinase 2 |
| Specificity: |
This is a highly specific antibody against HK2/Hexokinase 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hexokinase 2 |
| Gene ID Number: |
3099 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Four hexokinase isoenzymes have been identified, Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, Glucokinase lacks the N-terminal hydrophobic cluster, HXK I has been shown to be expressed in brain, HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues, HXK III has the highest affinity for glucose, Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids, Of the hexokinases, The hydrophobic cluster is thought to be necessary for membrane binding, This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases, also designated glucokinase or GCK), determining the â, hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, including hexokinase I (HXK I), kidney and heart tissues as well as in hepatoma cell lines, the conversion of glucose to glucose-6-phosphate, &euro, &euro, &oelig, The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, set pointâ, for insulin secretion |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the HK2/Hexokinase 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
HK2/Hexokinase 2 |
| Short name: |
HK2/Hexokinase 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, HK2/Hexokinase 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4923 |
| Gene: |
HK2 |
More about : HK2 |
| Long gene name: |
hexokinase 2 |
| Locus: |
2p12 |
| Discovery year: |
1993-03-11 |
| Entrez gene record: |
3099 |
| RefSeq identity: |
NM_000189 |
| Havana BLAST/BLAT: |
OTTHUMG00000129972 |