| Long name: |
ALEXA FLUOR 555 Conjugated, STXBP1/Munc18 Polyclonal Antibody |
| Also known as: |
Anti-STXBP1/Munc18 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
STXBP1/Munc18 |
| Specificity: |
This is a highly specific antibody against STXBP1/Munc18 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Munc18 |
| Gene ID Number: |
6812 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
2, It is essential for neurotransmission and binds syntaxin, It may play a role in determining the specificity of intracellular fusion reactions, Munc18 can interact with syntaxins 1, Munc18-1 has been shown to be primarily expressed in brain, Two Munc18 isoforms have recently been identified, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio, and 3 but not syntaxin 4, possibly through interaction with GTP binding proteins, while Munc18-2 is expressed in most tissues, Munc18 may participate in the regulation of synaptic vesicle docking and fusion, Mutations in Munc18 can result in accumulations of acetylcholine and paralytic phenotype suggestive of a neurotransmitter release defect |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
hUNC18 MUNC18-1 UNC18 rbSec1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
STXBP1/Munc18 |
| Short name: |
STXBP1/Munc18 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, syntaxin binding protein 1/Munc18 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GABAergic and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045921 and positive regulation of exocytosis and biological process this GO :0045956 and positive regulation of calcium ion-dependent exocytosis and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050796 and regulation of insulin secretion and biological process this GO :0050821 and protein stabilization and biological process this GO :0060292 and long term synaptic depression and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070527 and platelet aggregation and biological process, MUNC18-1 and NSEC1 and P67 and RBSEC1 and UNC18, Plasma membranes, STXBP1 and IDBG-638972 and ENSBTAG00000003525 and 282378, STXBP1 and IDBG-86143 and ENSG00000136854 and 6812, Stxbp1 and IDBG-161623 and ENSMUSG00000026797 and 20910, protein N-terminus binding, this GO :0000149 and SNARE binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0006887 and exocytosis and biological process this GO :0006904 and vesicle docking involved in exocytosis and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0007274 and neuromuscular synaptic transmission and biological process this GO :0007412 and axon target recognition and biological process this GO :0010807 and regulation of synaptic vesicle priming and biological process this GO :0014047 and glutamate secretion and biological process this GO :0015031 and protein transport and biological process this GO :0016188 and synaptic vesicle maturation and biological process this GO :0016192 and vesicle-mediated transport and biological process this GO :0017075 and syntaxin-1 binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0031091 and platelet alpha granule and cellular component this GO :0032229 and negative regulation of synaptic transmission, this GO :0000149 : SNARE binding, this GO :0000149 : SNARE binding and also this GO :0005515 : protein binding and also this GO :0017075 : syntaxin-1 binding and also this GO :0019901 : protein kinase binding and also this GO :0019904 : protein domain specific binding and also this GO :0019905 : syntaxin binding and also this GO :0042802 : identical protein binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0047485 : protein N-terminus binding, this GO :0005515 : protein binding, this GO :0017075 : syntaxin-1 binding, this GO :0019901 : protein kinase binding, this GO :0019904 : protein domain specific binding, this GO :0019905 : syntaxin binding, this GO :0042802 : identical protein binding, this GO :0044822 : poly(A) RNA binding, this GO :0047485 : protein N-terminus binding, syntaxin binding protein 1 |
| Identity: |
11444 |
| Gene: |
STXBP1 |
More about : STXBP1 |
| Long gene name: |
syntaxin binding protein 1 |
| Synonyms name: |
syntaxin-binding protein 1 |
| Locus: |
9q34, 11 |
| Discovery year: |
1996-12-27 |
| GenBank acession: |
AF004563 |
| Entrez gene record: |
6812 |
| Pubmed identfication: |
9545644 |
| RefSeq identity: |
NM_003165 |
| Havana BLAST/BLAT: |
OTTHUMG00000020713 |