| Long name: |
ALEXA FLUOR 594 Conjugated, 1 Polyclonal Antibody, CACNA1A/Cav2 |
| Also known as: |
1 PAb ALEXA FLUOR 594, Anti-CACNA1A/Cav2 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
1, CACNA1A/Cav2 |
| Specificity: |
1, This is a highly specific antibody against CACNA1A/Cav2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CACNA1A |
| Gene ID Number: |
773 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cav2, Cav2, In many cases, The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity, The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit, Voltage-dependent calcium channels are multisubunit complexes, alpha-2, beta and delta subunits in a 1:1:1:1 ratio, cell division and cell death, cell motility, consisting of alpha-1, gene expression, hormone or neurotransmitter release, including muscle contraction, this subunit is sufficient to generate voltage-sensitive calcium channel activity, 1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents, 1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family, 1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, Cav2 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Cav2, 1 EA2 APCA HPCA FHM |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
1, CACNA1A/Cav2 |
| Short name: |
1 Antibody, CACNA1A/Cav2 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, P/Q classification, a 1A subunit/Cav2, voltage-dependent, 1 (Antibody to), calcium channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
APCA and BI and CACNL1A4 and CAV2, CACNA1A and IDBG-31996 and ENSG00000141837 and 100507353, CACNA1A and IDBG-642817 and ENSBTAG00000014828 and 282648, Cacna1a and IDBG-174190 and ENSMUSG00000034656 and 12286, P/Q type, alpha 1A subunit, glutamatergic and biological process this GO :0042133 and neurotransmitter metabolic process and biological process this GO :0042391 and regulation of membrane potential and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0042995 and cell projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043113 and receptor clustering and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048265 and response to pain and biological process this GO :0048266 and behavioral response to pain and biological process this GO :0048791 and calcium ion-dependent exocytosis of neurotransmitter and biological process this GO :0048813 and dendrite morphogenesis and biological process this GO :0050770 and regulation of axonogenesis and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0050877 and neurological system process and biological process this GO :0050883 and musculoskeletal movement, metal ion binding, nuclei, spinal reflex action and biological process this GO :0050885 and neuromuscular process controlling balance and biological process this GO :0050905 and neuromuscular process and biological process this GO :0051899 and membrane depolarization and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060024 and rhythmic synaptic transmission and biological process this GO :0070509 and calcium ion import and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0086010 and membrane depolarization during action potential and biological process, this GO :0000096 and sulfur amino acid metabolic process and biological process this GO :0005216 and ion channel activity and molecular function this GO :0005244 and voltage-gated ion channel activity and molecular function this GO :0005245 and voltage-gated calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005891 and voltage-gated calcium channel complex and cellular component this GO :0006006 and glucose metabolic process and biological process this GO :0006112 and energy reserve metabolic process and biological process this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007214 and gamma-aminobutyric acid signaling pathway and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007270 and neuron-neuron synaptic transmission and biological process this GO :0007274 and neuromuscular synaptic transmission and biological process this GO :0007416 and synapse assembly and biological process this GO :0007628 and adult walking behavior and biological process this GO :0008219 and cell death and biological process this GO :0008331 and high voltage-gated calcium channel activity and molecular function this GO :0014051 and gamma-aminobutyric acid secretion and biological process this GO :0014056 and regulation of acetylcholine secretion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016049 and cell growth and biological process this GO :0017156 and calcium ion-dependent exocytosis and biological process this GO :0017158 and regulation of calcium ion-dependent exocytosis and biological process this GO :0019226 and transmission of nerve impulse and biological process this GO :0019905 and syntaxin binding and molecular function this GO :0021522 and spinal cord motor neuron differentiation and biological process this GO :0021590 and cerebellum maturation and biological process this GO :0021679 and cerebellar molecular layer development and biological process this GO :0021680 and cerebellar Purkinje cell layer development and biological process this GO :0021702 and cerebellar Purkinje cell differentiation and biological process this GO :0021750 and vestibular nucleus development and biological process this GO :0021953 and central nervous system neuron differentiation and biological process this GO :0030425 and dendrite and cellular component this GO :0030644 and cellular chloride ion homeostasis and biological process this GO :0032353 and negative regulation of hormone biosynthetic process and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0034765 and regulation of ion transmembrane transport and biological process this GO :0035249 and synaptic transmission, this GO :0005216 : ion channel activity, this GO :0005216 : ion channel activity and also this GO :0005244 : voltage-gated ion channel activity and also this GO :0005245 : voltage-gated calcium channel activity and also this GO :0005515 : protein binding and also this GO :0008331 : high voltage-gated calcium channel activity and also this GO :0019905 : syntaxin binding and also this GO :0046872 : metal ion binding, this GO :0005244 : voltage-gated ion channel activity, this GO :0005245 : voltage-gated calcium channel activity, this GO :0005515 : protein binding, this GO :0008331 : high voltage-gated calcium channel activity, this GO :0019905 : syntaxin binding, this GO :0046872 : metal ion binding, voltage-dependent, 1 and EA2 and FHM and HPCA and MHP and MHP1 and SCA6, 773, calcium channel |
| Identity: |
1388 |
| Gene: |
CACNA1A |
More about : CACNA1A |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 A |
| Synonyms gene: |
CACNL1A4 SCA6 MHP1 MHP |
| Synonyms gene name: |
P/Q type, alpha 1A subunit , calcium channel, voltage-dependent |
| Locus: |
19p13, 13 |
| Discovery year: |
1996-06-18 |
| GenBank acession: |
U79666 |
| Entrez gene record: |
773 |
| Pubmed identfication: |
8825650 16382099 23827678 |
| RefSeq identity: |
NM_000068 |
| Classification: |
Calcium voltage-gated channel subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000044590 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database Familial Hemiplegic Migraine (FHM) Variation Database LRG_7 |