| Long name: |
ALEXA FLUOR 488 Conjugated, Legumain Polyclonal Antibody |
| Also known as: |
Anti-Legumain PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Legumain |
| Specificity: |
This is a highly specific antibody against Legumain |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
225-275/433 |
| Subcellular location: |
Lysosome |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Legumain |
| Gene ID Number: |
5641 |
| Swiss Prot: |
Q99538 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Can also cleave aspartyl bonds slowly, May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system, Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity), Required for normal degradation of internalized EGFR, Required for normal lysosomal protein degradation in renal proximal tubules, especially under acidic conditions, Has a strict specificity for hydrolysis of asparaginyl bonds |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Legumain Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Legumain |
| Short name: |
Legumain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Legumain (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23079 |
| Gene: |
LGMNP1 |
More about : LGMNP1 |
| Long gene name: |
legumain pseudogene 1 |
| Synonyms gene: |
LGMN2P |
| Synonyms gene name: |
legumain 2 pseudogene |
| Locus: |
13q21, 31 |
| Discovery year: |
2003-09-03 |
| Entrez gene record: |
122199 |
| RefSeq identity: |
NG_001534 |
| Havana BLAST/BLAT: |
OTTHUMG00000017029 |