| Long name: |
FITC Conjugated, SOD4/CCS Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SOD4/CCS |
| Specificity: |
This is a highly specific antibody against SOD4/CCS |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SOD4 |
| Gene ID number: |
9973 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor, SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit, SOD3 is a heparin-binding multimer of disulfide-linked dimers, SOD4 is a copper chaperone for superoxide dismutase (CCS), Several classes of SOD have been identified, The manganese containing 80 kDa tetrameric enzyme SOD2, These include intracellular copper, Zn-SOD (EC-SOD/SOD-3), Zn-SOD/SOD-1), is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, primarily expressed in human lungs, the mitochondrial respiratory chain, vessel walls and airways, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase, which specifically delivers Cu to copper/zinc superoxide dismutase, zinc SOD (Cu, Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CCS_HUMAN, Copper chaperone for superoxide dismutase, MGC138260, SOD 4, SOD4, Superoxide dismutase copper chaperone, CCS |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SOD4/CCS Conjugated |
| Short name: |
FITC Conjugated, SOD4/CCS Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SOD4/CCS (Antibody to) |
| Alternative technique: |
antibodies |