| Long name: |
Biotin Conjugated, SOD4/CCS Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SOD4/CCS |
| Specificity: |
This is a highly specific antibody against SOD4/CCS |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SOD4 |
| Gene ID number: |
9973 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor, SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit, SOD3 is a heparin-binding multimer of disulfide-linked dimers, SOD4 is a copper chaperone for superoxide dismutase (CCS), Several classes of SOD have been identified, The manganese containing 80 kDa tetrameric enzyme SOD2, These include intracellular copper, Zn-SOD (EC-SOD/SOD-3), Zn-SOD/SOD-1), is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, primarily expressed in human lungs, the mitochondrial respiratory chain, vessel walls and airways, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase, which specifically delivers Cu to copper/zinc superoxide dismutase, zinc SOD (Cu, Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CCS_HUMAN, Copper chaperone for superoxide dismutase, MGC138260, SOD 4, SOD4, Superoxide dismutase copper chaperone, CCS |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SOD4/CCS Conjugated |
| Short name: |
Conjugated, SOD4/CCS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, SOD4/CCS (Antibody to) |
| Alternative technique: |
antibodies |