| Long name: |
ALEXA FLUOR 350 Conjugated, eIF3F Polyclonal Antibody |
| Also known as: |
Anti-e3F PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
e3F |
| Specificity: |
This is a highly specific antibody against e3F |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
135-185/357 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human eIF3F |
| Gene ID Number: |
8665 |
| Swiss Prot: |
O00303 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Deubiquitinates activated NOTCH1, The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation, The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC), promoting its nuclear import, thereby acting as a positive regulator of Notch signaling, which is required for several steps in the initiation of protein synthesis, Component of the eukaryotic translation initiation factor 3 (eIF-3) complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
eIF3-epsilon eIF3-p47 eIF3f |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
eIF3F |
| Short name: |
eIF3F Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, eIF3F (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3275 |
| Gene: |
EIF3F |
More about : EIF3F |
| Long gene name: |
eukaryotic translation initiation factor 3 subunit F |
| Synonyms gene: |
EIF3S5 |
| Synonyms gene name: |
47kDa eukaryotic translation initiation factor 3, eukaryotic translation initiation factor 3, subunit 5 epsilon, subunit F |
| Locus: |
11p15, 4 |
| Discovery year: |
1998-11-26 |
| GenBank acession: |
U94855 AK093511 |
| Entrez gene record: |
8665 |
| Pubmed identfication: |
9341143 |
| RefSeq identity: |
NM_003754 |
| Classification: |
Eukaryotic translation initiation factor 3 |
| Havana BLAST/BLAT: |
OTTHUMG00000165675 |