| Long name: |
ALEXA FLUOR 555 Conjugated, PABP (Methyl Arg455/460) Antibody |
| Also known as: |
Anti-PABP Methyl Arg455/460 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PABP Methyl Arg455/460 |
| Specificity: |
This is a highly specific antibody against PABP Methyl Arg455/460 |
| Modification: |
Methylation |
| Modification Site: |
Methyl Arg455/460 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
440-480/636 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic metylpeptide derived from human PABP around metylation site of Arg455/Arg460 |
| Gene ID Number: |
26986 |
| Swiss Prot: |
P11940 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo, Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain, Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons, Involved in translationally coupled mRNA turnover, Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2, May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing, for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed, including that of its own transcript, Binds the poly(A) tail of mRNA |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
PABP, PABP-1, PABP1, PABPC1, PABPC2, PABPL1, Poly(A)-binding protein 1, Polyadenylate-binding protein 1, PAB1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Description: |
All three forms are highly reactive and rarely observed, CH3, In , It is a very stable group in most molecules, Such hydrocarbon , The anion has eight valence electrons, While the methyl group is usually part of a larger , containing one , it can be found on its own in any of three forms , the group is often , the radical seven and the cation six, , A , Me, abbreviated , alkyl , anion, atom , atoms &mdash, bonded , carbon , cation , derived from , formulas, groups occur in many , hydrogen , is an , methane, methyl group , molecule, or , organic compounds, radical, to three |
| Gene target: |
PABP (Methyl Arg455/460) |
| Short name: |
PABP (Methyl Arg455/460) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, PABP (Methyl Arg455/460) (Antibody to) |
| Alternative technique: |
antibodies |