| Long name: |
Biotin Conjugated, JMJD1B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
JMJD1B |
| Specificity: |
This is a highly specific antibody against JMJD1B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human JMJD1B |
| Gene ID number: |
51780 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
5qNCA (5q Nuclear Co-Activator) or C5orf7, Eptopic expression of JMJD1B exhibits growth suppressive activities, Expressed in a wide variety of tissues, JMJD1B functions as a histone demethylase and, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif, The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias, This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia, This suggests that JMJD1B plays a central role in the histone code, also known as KDM3B, demethylates lysine-9 of Histone H3, further supporting a role for JMJD1B in tumor suppression, is a member of the JHDM2 histone demethylase family of proteins, using iron as a cofactor, JMJD1B (jumonji domain containing 1B) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIAA1082 NET22 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
JMJD1B Conjugated |
| Short name: |
Conjugated, JMJD1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, JMJD1B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1337 |
| Gene: |
KDM3B |
More about : KDM3B |
| Long gene name: |
lysine demethylase 3B |
| Synonyms gene: |
C5orf7 JMJD1B |
| Synonyms gene name: |
chromosome 5 open reading frame 7 jumonji domain containing 1B lysine (K)-specific demethylase 3B |
| Locus: |
5q31, 2 |
| Discovery year: |
2000-07-21 |
| GenBank acession: |
AF251039 |
| Entrez gene record: |
51780 |
| Pubmed identfication: |
15138608 |
| RefSeq identity: |
NM_016604 |
| Classification: |
Lysine demethylases |
| Havana BLAST/BLAT: |
OTTHUMG00000163469 |