| Long name: |
ALEXA FLUOR 555 Conjugated, JMJD1B Polyclonal Antibody |
| Also known as: |
Anti-JMJD1B PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
JMJD1B |
| Specificity: |
This is a highly specific antibody against JMJD1B |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JMJD1B |
| Gene ID Number: |
51780 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
5qNCA (5q Nuclear Co-Activator) or C5orf7, Eptopic expression of JMJD1B exhibits growth suppressive activities, Expressed in a wide variety of tissues, JMJD1B functions as a histone demethylase and, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif, The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias, This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia, This suggests that JMJD1B plays a central role in the histone code, also known as KDM3B, demethylates lysine-9 of Histone H3, further supporting a role for JMJD1B in tumor suppression, is a member of the JHDM2 histone demethylase family of proteins, using iron as a cofactor, JMJD1B (jumonji domain containing 1B) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
KIAA1082 NET22 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
JMJD1B |
| Short name: |
JMJD1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, JMJD1B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1337 |
| Gene: |
KDM3B |
More about : KDM3B |
| Long gene name: |
lysine demethylase 3B |
| Synonyms gene: |
C5orf7 JMJD1B |
| Synonyms gene name: |
chromosome 5 open reading frame 7 jumonji domain containing 1B lysine (K)-specific demethylase 3B |
| Locus: |
5q31, 2 |
| Discovery year: |
2000-07-21 |
| GenBank acession: |
AF251039 |
| Entrez gene record: |
51780 |
| Pubmed identfication: |
15138608 |
| RefSeq identity: |
NM_016604 |
| Classification: |
Lysine demethylases |
| Havana BLAST/BLAT: |
OTTHUMG00000163469 |