| Long name: |
Biotin Conjugated, GDF15/MIC-1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GDF15/MIC-1 |
| Specificity: |
This is a highly specific antibody against GDF15/MIC-1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
260-308/308 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human GDF-15 |
| Gene ID number: |
9518 |
| Swiss Prot: |
Q99988 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues, In general, It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects, they are regulators of cell growth and differentiation in both embryonic and adult tissues, GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53, Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PLAB MIC-1 PDF MIC1 NAG-1 PTGFB |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GDF15/MIC-1 Conjugated |
| Short name: |
Conjugated, GDF15/MIC-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, growth differentiation factor 15/MIC-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GDF-15 and MIC-1 and MIC1 and NAG-1 and PDF and PLAB and PTGFB, GDF15 and IDBG-38078 and ENSG00000130513 and 9518, GDF15 and IDBG-641726 and ENSBTAG00000015618 and 618677, Gdf15 and IDBG-163724 and ENSMUSG00000038508 and 23886, growth factor activity, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008083 and growth factor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008083 : growth factor activity, this GO :0008083 : growth factor activity, growth differentiation factor 15 |
| Identity: |
30142 |
| Gene: |
GDF15 |
More about : GDF15 |
| Long gene name: |
growth differentiation factor 15 |
| Synonyms name: |
prostate differentiation factor |
| Locus: |
19p13, 11 |
| Discovery year: |
2004-02-12 |
| GenBank acession: |
BC008962 |
| Entrez gene record: |
9518 |
| Pubmed identfication: |
11895857 9593718 |
| RefSeq identity: |
NM_004864 |
| Havana BLAST/BLAT: |
OTTHUMG00000183360 |