| Long name: |
ALEXA FLUOR 488 Conjugated, GDF15/MIC-1 Polyclonal Antibody |
| Also known as: |
Anti-GDF15/MIC-1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GDF15/MIC-1 |
| Specificity: |
This is a highly specific antibody against GDF15/MIC-1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
260-308/308 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDF-15 |
| Gene ID Number: |
9518 |
| Swiss Prot: |
Q99988 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues, In general, It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects, they are regulators of cell growth and differentiation in both embryonic and adult tissues, GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53, Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PLAB MIC-1 PDF MIC1 NAG-1 PTGFB |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GDF15/MIC-1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GDF15/MIC-1 |
| Short name: |
GDF15/MIC-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, growth differentiation factor 15/MIC-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GDF-15 and MIC-1 and MIC1 and NAG-1 and PDF and PLAB and PTGFB, GDF15 and IDBG-38078 and ENSG00000130513 and 9518, GDF15 and IDBG-641726 and ENSBTAG00000015618 and 618677, Gdf15 and IDBG-163724 and ENSMUSG00000038508 and 23886, growth factor activity, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008083 and growth factor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008083 : growth factor activity, this GO :0008083 : growth factor activity, growth differentiation factor 15 |
| Identity: |
30142 |
| Gene: |
GDF15 |
More about : GDF15 |
| Long gene name: |
growth differentiation factor 15 |
| Synonyms name: |
prostate differentiation factor |
| Locus: |
19p13, 11 |
| Discovery year: |
2004-02-12 |
| GenBank acession: |
BC008962 |
| Entrez gene record: |
9518 |
| Pubmed identfication: |
11895857 9593718 |
| RefSeq identity: |
NM_004864 |
| Havana BLAST/BLAT: |
OTTHUMG00000183360 |