| Long name: |
ALEXA FLUOR 555 Conjugated, Villin Polyclonal Antibody |
| Also known as: |
Anti-Villin PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Villin |
| Specificity: |
This is a highly specific antibody against Villin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
345-395/827 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Villin |
| Gene ID Number: |
7429 |
| Swiss Prot: |
P09327 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Appears to regulate cell death by maintaining mitochondrial integrity, Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities, Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity, Binds phosphatidylinositol 4, Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, Plays a role in the actin nucleation, Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium, Regulates the intestinal epithelial cell morphology, Upon S, actin filament bundle assembly, actin filament capping and severing, binds LPA with higher affinity than PIP2, cell invasion, cell migration and apoptosis, chemotaxis and wound repair, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination, 5-bisphosphate (PIP2) and lysophosphatidic acid (LPA), Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments, flexneri cell infection |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
Villin |
| Short name: |
Villin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, Villin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30906 |
| Gene: |
VILL |
More about : VILL |
| Long gene name: |
villin like |
| Locus: |
3p22, 2 |
| Discovery year: |
2004-07-28 |
| Entrez gene record: |
50853 |
| Pubmed identfication: |
9179494 |
| RefSeq identity: |
NM_015873 |
| Classification: |
Gelsolin/villins |
| Havana BLAST/BLAT: |
OTTHUMG00000130814 |