| Long name: |
Villin Primary Polyclonal Antibody |
| Also known as: |
Villin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Villin |
| Specificity: |
This is a highly specific antibody against Villin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
345-395/827 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Villin |
| Gene ID number: |
7429 |
| Swiss Prot: |
P09327 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Appears to regulate cell death by maintaining mitochondrial integrity, Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities, Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity, Binds phosphatidylinositol 4, Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, Plays a role in the actin nucleation, Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium, Regulates the intestinal epithelial cell morphology, Upon S, actin filament bundle assembly, actin filament capping and severing, binds LPA with higher affinity than PIP2, cell invasion, cell migration and apoptosis, chemotaxis and wound repair, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination, 5-bisphosphate (PIP2) and lysophosphatidic acid (LPA), Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments, flexneri cell infection |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
D2S1471, VIL1, Villin-1, VIL |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Villin |
| Short name: |
Villin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Villin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30906 |
| Gene: |
VILL |
More about : VILL |
| Long gene name: |
villin like |
| Locus: |
3p22, 2 |
| Discovery year: |
2004-07-28 |
| Entrez gene record: |
50853 |
| Pubmed identfication: |
9179494 |
| RefSeq identity: |
NM_015873 |
| Classification: |
Gelsolin/villins |
| Havana BLAST/BLAT: |
OTTHUMG00000130814 |