| Long name: |
FITC Conjugated, DIO2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DIO2 |
| Specificity: |
This is a highly specific antibody against DIO2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DIO2 |
| Gene ID number: |
1734 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DIO2 is expressed in heart, It is essential for providing the brain with appropriate levels of T3 during the critical period of development, There are two named isoforms, fetal brain and several regions of the adult brain, placenta, skeletal muscle, 3', 3'-triiodothyronine), 5, 5, 5'-tetraiodothyronine) into T3 (3, DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
TXDI2 SelY |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DIO2 Conjugated |
| Short name: |
FITC Conjugated, DIO2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, iodothyronine, type II (Antibody to), deiodinase |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
5DII and D2 and DIOII and SelY and TXDI2, DIO2 and IDBG-14346 and ENSG00000211448 and 1734, DIO2 and IDBG-646906 and ENSBTAG00000001605 and 494548, Dio2 and IDBG-161130 and ENSMUSG00000007682 and 13371, Plasma membranes, iodothyronine, this GO :0001514 and selenocysteine incorporation and biological process this GO :0004800 and thyroxine 5'-deiodinase activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006590 and thyroid hormone generation and biological process this GO :0008430 and selenium binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016209 and antioxidant activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042403 and thyroid hormone metabolic process and biological process this GO :0042404 and thyroid hormone catabolic process and biological process this GO :0042446 and hormone biosynthetic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process, this GO :0004800 : thyroxine 5'-deiodinase activity, this GO :0004800 : thyroxine 5'-deiodinase activity and also this GO :0008430 : selenium binding and also this GO :0016209 : antioxidant activity and also this GO :0016491 : oxidoreductase activity and also this GO :0031625 : ubiquitin protein ligase binding, this GO :0008430 : selenium binding, this GO :0016209 : antioxidant activity, this GO :0016491 : oxidoreductase activity, this GO :0031625 : ubiquitin protein ligase binding, type II, ubiquitin protein ligase binding, deiodinase |
| Identity: |
2884 |
| Gene: |
DIO2 |
More about : DIO2 |
| Long gene name: |
iodothyronine deiodinase 2 |
| Synonyms gene name: |
deiodinase, iodothyronine type II |
| Synonyms name: |
thyroxine deiodinase, type II deiodonase-2 deiodinase-2 |
| Locus: |
14q31, 1 |
| Discovery year: |
1997-05-09 |
| GenBank acession: |
AF007144 |
| Entrez gene record: |
1734 |
| Pubmed identfication: |
8755651 10343107 |
| Classification: |
Selenoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000171443 |