| Long name: |
FITC Conjugated, HSP22 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HSP22 |
| Specificity: |
This is a highly specific antibody against HSP22 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HSP22 |
| Gene ID number: |
26353 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Hsp22 is a monomeric protein which interacts with HSPB1, It displays temperature-dependent chaperone activity, Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, The highest abundance of Hsp22 is in skeletal muscle, and placenta, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L), heart, Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
H11 E2IG1 HSP22 HspB8 CMT2L |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HSP22 Conjugated |
| Short name: |
FITC Conjugated, HSP22 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, HSP22 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30171 |
| Gene: |
HSPB8 |
More about : HSPB8 |
| Long gene name: |
heat shock protein family B (small) member 8 |
| Synonyms gene name: |
heat shock 27kDa protein 8 heat shock 22kDa protein 8 |
| Locus: |
12q24, 23 |
| Discovery year: |
2004-01-29 |
| GenBank acession: |
AF191017 |
| Entrez gene record: |
26353 |
| Pubmed identfication: |
10833516 11085516 |
| RefSeq identity: |
NM_014365 |
| Classification: |
Small heat shock proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000168932 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_249 |