| Long name: |
HSP22 Primary Polyclonal Antibody |
| Also known as: |
HSP22 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HSP22 |
| Specificity: |
This is a highly specific antibody against HSP22 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSP22 |
| Gene ID number: |
26353 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Hsp22 is a monomeric protein which interacts with HSPB1, It displays temperature-dependent chaperone activity, Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, The highest abundance of Hsp22 is in skeletal muscle, and placenta, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L), heart, Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Alpha crystallin C chain, CRYAC, Charcot Marie Tooth disease axonal type 2L, Charcot Marie Tooth disease spinal, DHMN 2, DHMN2, E2 induced gene 1 protein, E2IG1, H11, HMN 2, HMN2, HSB8, HSPB 8, HSPB8, Heat shock 22kDa protein 8, Heat shock protein 22, Heat shock protein beta 8, Hereditary motor neuropathy distal, Protein kinase H11, Small stress protein like protein HSP22, Spinal muscular atrophy distal adult autosomal dominant, CMT2L |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HSP22 |
| Short name: |
HSP22 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HSP22 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30171 |
| Gene: |
HSPB8 |
More about : HSPB8 |
| Long gene name: |
heat shock protein family B (small) member 8 |
| Synonyms gene name: |
heat shock 27kDa protein 8 heat shock 22kDa protein 8 |
| Synonyms: |
H11 E2IG1 HSP22 HspB8 CMT2L |
| Locus: |
12q24, 23 |
| Discovery year: |
2004-01-29 |
| GenBank acession: |
AF191017 |
| Entrez gene record: |
26353 |
| Pubmed identfication: |
10833516 11085516 |
| RefSeq identity: |
NM_014365 |
| Classification: |
Small heat shock proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000168932 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_249 |