| Long name: |
ALEXA FLUOR 594 Conjugated, KEAP1 Polyclonal Antibody |
| Also known as: |
Anti-KEAP1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KEAP1 |
| Specificity: |
This is a highly specific antibody against KEAP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
75-125/624 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KEAP1 |
| Gene ID Number: |
9817 |
| Swiss Prot: |
Q14145 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol, Targets PGAM5 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression, Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0132 MGC10630 MGC1114 MGC20887 MGC4407 MGC9454 INrf2 KLHL19 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
KEAP1 |
| Short name: |
KEAP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, KEAP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23177 |
| Gene: |
KEAP1 |
More about : KEAP1 |
| Long gene name: |
kelch like ECH associated protein 1 |
| Synonyms name: |
kelch-like family member 19 |
| Locus: |
19p13, 2 |
| Discovery year: |
2003-09-30 |
| GenBank acession: |
AF361886 |
| Entrez gene record: |
9817 |
| RefSeq identity: |
NM_012289 |
| Classification: |
BTB domain containing Kelch like |
| Havana BLAST/BLAT: |
OTTHUMG00000180579 |