KEAP1 Antibody

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Catalog number: F40464-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: KEAP1 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1mg 389€ 0.1ml 263€ 1 vial 486€ 1 x 1 vial 411€ 100ul 630€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: KEAP1
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, IHC, WB
Recommended dilutions: IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
Notes: Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use: This KEAP1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q14145
Purity: Antigen affinity
Description: Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol, Targets PGAM5 for ubiquitination and degradation by the proteasome [UniProt], thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression, KEAP1 acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome
Immunogen: A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot the KEAP1 antibody and store frozen at -20 deg, Store at 4oC for up to one month
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: KEAP1
Short name: KEAP1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: KEAP1 (Antibody to)
Alternative technique: antibodies
Identity: 23177
Gene: KEAP1 | More about : KEAP1
Long gene name: kelch like ECH associated protein 1
Synonyms: KIAA0132 MGC10630 MGC1114 MGC20887 MGC4407 MGC9454 INrf2 KLHL19
Synonyms name: kelch-like family member 19
Locus: 19p13, 2
Discovery year: 2003-09-30
GenBank acession: AF361886
Entrez gene record: 9817
RefSeq identity: NM_012289
Classification: BTB domain containing Kelch like
Havana BLAST/BLAT: OTTHUMG00000180579

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