| Long name: |
ALEXA FLUOR 488 Conjugated, Talin Polyclonal Antibody |
| Also known as: |
Anti-Talin1 + 2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Talin1 + 2 |
| Specificity: |
This is a highly specific antibody against Talin1 + 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1610-1660/2541 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Talin 1 |
| Gene ID Number: |
7094, 83660 |
| Swiss Prot: |
Q9Y490, Q9Y4G6 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
At physiological ionic strength, In cultured cells, It is localized at a subset of adherens junctions, Talin and vinculin have been shown to interact with each other and both have been proposed to be involved in generating the transmembrane connection, Talin interacts with at least two other proteins that are localized at adhesion plaques, a multifunctional constituent of cell-substratum attachment sites, between the extracellular matrix and the cytoskeleton, flexible, is a high molecular weight protein (225-270 kDa) found in variety of tissues and cell types, monomeric protein with the ability to self-associate into dimers at higher protein concentrations, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin, talin is an elongate, that occurs at adhesion plaques, vinculin and integrin, Talin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
ILWEQ |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Talin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Talin |
| Short name: |
Talin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Talin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11845 |
| Gene: |
TLN1 |
More about : TLN1 |
| Long gene name: |
talin 1 |
| Synonyms gene: |
TLN |
| Locus: |
9p13, 3 |
| Discovery year: |
1996-10-31 |
| GenBank acession: |
AB028950 |
| Entrez gene record: |
7094 |
| Pubmed identfication: |
7635475 10610730 |
| RefSeq identity: |
NM_006289 |
| Classification: |
FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019874 |