| known also as: |
alpha1 PI), alpha1 Proteinase Inhibitor, Anti-a1-Antitrypsin (AAT |
| known also as: |
alpha1 PI), alpha1 Proteinase Inhibitor, a1-Antitrypsin (AAT |
| known also as: |
alpha1 PI), alpha1 Proteinase Inhibitor, a1-Antitrypsin (AAT |
| known also as: |
a1-Antitrypsin |
| known also as: |
alpha1 PI), alpha1 Proteinase Inhibitor, Anti -a1-Antitrypsin (AAT |
| Other names: |
Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Alpha-1-antitrypsin, Serpin A1, alpha-1 protease inhibitor, alpha-1-antiproteinase, alpha-1-antitrypsin, alpha-1-antitrypsin, alpha-1-antitrypsin null, antitrypsin), clade A, clade A (alpha-1 antiproteinase, member 1, member 1, protease inhibitor 1 (anti-elastase), serine (or cysteine) proteinase inhibitor, serpin A1, serpin peptidase inhibitor, alpha-1-antitrypsin |
| Other gene names: |
A1A, A1AT, AAT, AAT, PI, PI, PI1, PRO2275, SERPINA1, SPAAT, alpha1AT, SERPINA1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
A single precipitin arc is observed with normal plasma of identical mobility to that obtained with purified alpha1AT, Specific for alpha1AT as demonstrated by immunoelectrophoresis |
| Purification method: |
and solid -phase adsorption to remove unwanted crossreactivity, Purified by caprylic acid and ammonium sulfate precipitations |
| Form/Appearance: |
0, pH7, 1M sodium chloride and 50% glycerol, 4, Supplied in 10mM HEPES |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage, For maximum recovery of product, For optimal long term storage, Further dilutions can be made in assay buffer, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
alpha1 PI), alpha1 Proteinase Inhibitor, a1-Antitrypsin (AAT |
| Short name: |
alpha1 PI), alpha1 Proteinase Inhibitor, a1-Antitrypsin (AAT |
| Alternative name: |
alpha1 PI), alpha1 Proteinase suppressor, a1-Antitrypsin (AAT |
| Identity: |
8941 |
| Gene: |
SERPINA1 |
More about : SERPINA1 |
| Long gene name: |
serpin family A member 1 |
| Synonyms gene: |
PI |
| Synonyms gene name: |
antitrypsin), antitrypsin), clade A (alpha-1 antiproteinase, clade A (alpha-1 antiproteinase, member 1 , member 1 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor |
| Synonyms: |
AAT A1A PI1 alpha-1-antitrypsin A1AT alpha1AT |
| Synonyms name: |
alpha-1-antitrypsin , protease inhibitor 1 (anti-elastase) |
| Locus: |
14q32, 13 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X01683 |
| Entrez gene record: |
5265 |
| Pubmed identfication: |
24172014 |
| RefSeq identity: |
NM_001002235 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000150355 |