| Catalog number: | bs-3459R |
|---|---|
| Price: | 347 € |
| Supplier: | acr |
| Product name: | Tuberin (Ser1254) Antibody |
| Quantity: | 50 Вµg |
| Related search: |
| Long name: | Tuberin (Ser1254) Primary Polyclonal Antibody |
|---|---|
| Also known as: | Tuberin (Ser1254) PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | Tuberin Ser1254 |
| Specificity: | This is a highly specific antibody against Tuberin Ser1254 |
| Modification(s): | Phosphorylation |
| Modification site(s): | Ser1254 |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser1254 [SL(p-S)VP] |
| Gene ID number: | 7249 |
| Tested Applications: | IF(IHC-P), IHC-P |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | At least three isoforms of Tuberin exist, Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking, It may function in vesicular transport, It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, Mutations in tuberin lead to constitutive activation of RAP1A in tumors, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors, is implicated as a tumor suppressor, or TSC2 (Tuberous sclerosis complex), suggesting a possible mechanism for its role in regulating cellular growth, Tuberin |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | LAM, P-TSC2 Ser1254FLJ43106, P-Tuberin/TSC2 Ser1254, TSC2, TSC2 Ser1254, TSC2_HUMAN, TSC4, Tuberin, Tuberous sclerosis 2 protein, Tuberin Ser1254 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | Tuberin (Ser1254) |
| Short name: | Tuberin (Ser1254) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | Tuberin (Ser1254) (Antibody to) |
| Alternative technique: | antibodies |
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