| Long name: |
TOPO II Alpha (Ser1106) Antibody |
| Also known as: |
TOPO II Alpha (Ser1106) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TOPO II Alpha Ser1106 |
| Specificity: |
This is a highly specific antibody against TOPO II Alpha Ser1106 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser1106 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human TOPO II Alpha around the phosphorylation site of Ser1106 |
| Gene ID number: |
7153 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, Reduced activity of this enzyme may also play a role in ataxia-telangiectasia, The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance, The gene encoding this form, This nuclear enzyme is involved in processes such as chromosome condensation, Two forms of this enzyme exist as likely products of a gene duplication event, alpha, an enzyme that controls and alters the topologic states of DNA during transcription, and the relief of torsional stress that occurs during DNA transcription and replication, chromatid separation, is localized to chromsome 17 and the beta gene is localized to chromosome 3, thus altering the topology of DNA, This gene encodes a DNA topoisomerase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DNA Topoisomerase2, DNA topoisomerase 2-alpha, DNA topoisomerase II, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, TOP 2A, TOP2, TOP2A, TOP2A_HUMAN, TP2A, TopII alpha, Topo II alpha, Topoisomerase DNA II alpha 170kDa, Topoisomerase II alpha 170 kDa, alpha isozyme, &hellip, ¡, DNA topoisomeraseâ, alpha |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The TOPO II Alpha (Ser1106) Antibody is a &alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TOPO II Alpha (Ser1106) |
| Short name: |
TOPO II Alpha (Ser1106) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TOPO II a (Ser1106) (Antibody to) |
| Alternative technique: |
antibodies |