| Long name: |
ALEXA FLUOR 647 Conjugated, Ret (Tyr905) Polyclonal Antibody |
| Also known as: |
Anti-Ret Tyr905 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Ret Tyr905 |
| Specificity: |
This is a highly specific antibody against Ret Tyr905 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr905 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Ret around the phosphorylation site of Tyr905 |
| Gene ID Number: |
5979 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Active in the absence of ligand, Acts as a dependence receptor, ITGB1 and ITGB3)-dependent manner, Involved in the development of the neural crest, Mediator of several diseases such as neuroendocrine cancers, Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an integrin (e, Phosphorylates PTK2/FAK1, Regulates both cell death/survival balance and positional information, Regulates nociceptor survival and size, Required for the molecular mechanisms orchestration during intestine organogenesis, Triggers the differentiation of rapidly adapting (RA) mechanoreceptors, a major component of the gut-associated lymphoid tissue, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands, and promotes the formation of Peyer's patch-like structures, but triggers apoptosis in absence of GDNF, cell migration, in the presence of the ligand GDNF in somatotrophs (within pituitary), involved in the development of enteric nervous system and renal organogenesis during embryonic life, neuronal navigation, promotes survival and down regulates growth hormone (GH) production, these diseases are characterized by aberrant integrins-regulated cell migration, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage, Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, g |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CDHF 12, CDHF12, CDHR16, Cadherin family member 12, Cadherin related family member 16, ELKS Fusion gene, HSCR 1, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC 1, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, PTC, Proto oncogene tyrosine protein kinase receptor ret, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, RET, RET ELE1, RET transforming sequence, RET51, RET9, RET_HUMAN, Ret Proto oncogene, tyrosine-protein kinase receptor ret, C ret |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Ret (Tyr905) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Ret (Tyr905) |
| Short name: |
Ret (Tyr905) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ret proto-oncogene (Tyr905) (Antibody to) |
| Alternative technique: |
antibodies |