| Long name: |
Cy7 Conjugated, Ret (Tyr905) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Ret Tyr905 |
| Specificity: |
This is a highly specific antibody against Ret Tyr905 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr905 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Ret around the phosphorylation site of Tyr905 |
| Gene ID number: |
5979 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Active in the absence of ligand, Acts as a dependence receptor, ITGB1 and ITGB3)-dependent manner, Involved in the development of the neural crest, Mediator of several diseases such as neuroendocrine cancers, Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an integrin (e, Phosphorylates PTK2/FAK1, Regulates both cell death/survival balance and positional information, Regulates nociceptor survival and size, Required for the molecular mechanisms orchestration during intestine organogenesis, Triggers the differentiation of rapidly adapting (RA) mechanoreceptors, a major component of the gut-associated lymphoid tissue, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands, and promotes the formation of Peyer's patch-like structures, but triggers apoptosis in absence of GDNF, cell migration, in the presence of the ligand GDNF in somatotrophs (within pituitary), involved in the development of enteric nervous system and renal organogenesis during embryonic life, neuronal navigation, promotes survival and down regulates growth hormone (GH) production, these diseases are characterized by aberrant integrins-regulated cell migration, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage, Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, g |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
CDHF 12, CDHF12, CDHR16, Cadherin family member 12, Cadherin related family member 16, ELKS Fusion gene, HSCR 1, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC 1, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, PTC, Proto oncogene tyrosine protein kinase receptor ret, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, RET, RET ELE1, RET transforming sequence, RET51, RET9, RET_HUMAN, Ret Proto oncogene, tyrosine-protein kinase receptor ret, C ret |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
Ret (Tyr905) Conjugated |
| Short name: |
Conjugated, Ret (Tyr905) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, ret proto-oncogene (Tyr905) (Antibody to) |
| Alternative technique: |
antibodies |