| Long name: |
Rad17 (Ser645) Primary Polyclonal Antibody |
| Also known as: |
Rad17 (Ser645) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Rad17 Ser645 |
| Specificity: |
This is a highly specific antibody against Rad17 Ser645 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser645 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Rad17 around the phosphorylation site of Ser645 |
| Gene ID number: |
5884 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Jul 2013], Multiple alternatively spliced transcript variants of this gene, The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage, This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, This protein shares strong similarity with DNA replication factor C (RFC), Two pseudogenes, [provided by RefSeq, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage, and can form a complex with RFCs, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells, have been identified, have been reported, located on chromosomes 7 and 13, which encode four distinct protein isoforms, which may be required for its phosphorylation, The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cell cycle checkpoint protein, Cell cycle checkpoint protein RAD17, HRAD 17, HRAD17, R24L, RAD1 S, RAD17 homolog, RAD17Sp, RF C activator 1 homolog, RF C/activator 1 homolog, Rad 17, Rad 24, Rad17 like protein, Rad24, pombe homolog, CCYC |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Rad17 (Ser645) |
| Short name: |
Rad17 (Ser645) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Rad17 (Ser645) (Antibody to) |
| Alternative technique: |
antibodies |