| Long name: |
PE Conjugated, NMDAR2B (Tyr1070) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
PE |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NMDAR2B Tyr1070 |
| Specificity: |
This phosphorylated site is homologous to that of Tyr1070 in Mouse and Rat, This is a highly specific antibody against NMDAR2B Tyr1070 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr1070 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1040-1090/1484 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1070 |
| Gene ID number: |
2904 |
| Swiss Prot: |
Q13224 |
| Tested applications: |
FCM |
| Recommended dilutions: |
FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
480, 565nm/578nm |
| Synonyms: |
GluN2B |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NMDAR2B (Tyr1070) PE Conjugated |
| Short name: |
PE Conjugated, NMDAR2B (Tyr1070) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
PE |
| Alternative name: |
peroxidase coupled, NMDAR2B (Tyr1070) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4586 |
| Gene: |
GRIN2B |
More about : GRIN2B |
| Long gene name: |
glutamate ionotropic receptor NMDA type subunit 2B |
| Synonyms gene: |
NMDAR2B |
| Synonyms gene name: |
N-methyl D-aspartate 2B , glutamate receptor, ionotropic |
| Locus: |
12p13, 1 |
| Discovery year: |
1992-09-18 |
| Entrez gene record: |
2904 |
| Pubmed identfication: |
1350383 |
| Classification: |
Glutamate ionotropic receptor NMDA type subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000137373 |