MSK1 (Ser376) Antibody, ALEXA FLUOR 488

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Catalog number: bs-3283R-A488
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: MSK1 (Ser376) Antibody, ALEXA FLUOR 488
Quantity: 100ul
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Long name: ALEXA FLUOR 488 Conjugated, MSK1 (Ser376) Polyclonal Antibody
Also known as: Anti-MSK1 Ser376 PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: MSK1 Ser376
Specificity: This is a highly specific antibody against MSK1 Ser376
Modification: Phosphorylation
Modification Site: Ser376
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 370-385/802
Subcellular location: Nucleus, Cytoplasm
Source: KLH conjugated synthetic phosphopeptide derived from human MSK1 around the phosphorylation site of Ser376 [GY(p-S)FV]
Gene ID Number: 9252
Swiss Prot: O75582
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: ATF1 H3 and HMG14 in response to mitogen and stress, It is also known to be required for the phosphorylation of CREB, MSK1 autophosphorylate on at least 5 sites, MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase, MSK1 contains two kinase domains (N term and a C term), Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain, Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, Similar to RSK, MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: MSK1 RLPK
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MSK1 (Ser376) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: MSK1 (Ser376)
Short name: MSK1 (Ser376) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, MSK1 (Ser376) (Antibody to)
Alternative technique: antibodies
Identity: 10434
Gene: RPS6KA5 | More about : RPS6KA5
Long gene name: ribosomal protein S6 kinase A5
Synonyms gene name: 90kD, polypeptide 5 , ribosomal protein S6 kinase
Locus: 14q32, 11
Discovery year: 1999-03-10
GenBank acession: AF074393
Entrez gene record: 9252
Pubmed identfication: 9687510 10702687
RefSeq identity: NM_004755
Classification: Mitogen-activated protein kinase-activated protein kinases
Havana BLAST/BLAT: OTTHUMG00000171055

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