| Catalog number: | bs-3283R-A488 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | MSK1 (Ser376) Antibody, ALEXA FLUOR 488 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, MSK1 (Ser376) Polyclonal Antibody |
|---|---|
| Also known as: | Anti-MSK1 Ser376 PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | MSK1 Ser376 |
| Specificity: | This is a highly specific antibody against MSK1 Ser376 |
| Modification: | Phosphorylation |
| Modification Site: | Ser376 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 370-385/802 |
| Subcellular location: | Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic phosphopeptide derived from human MSK1 around the phosphorylation site of Ser376 [GY(p-S)FV] |
| Gene ID Number: | 9252 |
| Swiss Prot: | O75582 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | ATF1 H3 and HMG14 in response to mitogen and stress, It is also known to be required for the phosphorylation of CREB, MSK1 autophosphorylate on at least 5 sites, MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase, MSK1 contains two kinase domains (N term and a C term), Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain, Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, Similar to RSK, MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Synonyms: | MSK1 RLPK |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MSK1 (Ser376) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | MSK1 (Ser376) |
| Short name: | MSK1 (Ser376) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, MSK1 (Ser376) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 10434 |
| Gene: | RPS6KA5 | More about : RPS6KA5 |
| Long gene name: | ribosomal protein S6 kinase A5 |
| Synonyms gene name: | 90kD, polypeptide 5 , ribosomal protein S6 kinase |
| Locus: | 14q32, 11 |
| Discovery year: | 1999-03-10 |
| GenBank acession: | AF074393 |
| Entrez gene record: | 9252 |
| Pubmed identfication: | 9687510 10702687 |
| RefSeq identity: | NM_004755 |
| Classification: | Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT: | OTTHUMG00000171055 |
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