GAB2 (Tyr643) Antibody, Cy5.5 Conjugated

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Catalog number: bs-3182R-Cy5.5
Price: 368 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: GAB2 (Tyr643) Antibody, Cy5.5 Conjugated
Quantity: 0.1ml
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Long name: Cy5, 5 Conjugated, GAB2 (Tyr643) Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy5, 5, 5, Cy5
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: GAB2 Tyr643
Specificity: This is a highly specific antibody against GAB2 Tyr643
Modification: Phosphorylation
Modification site: Tyr643
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Thr643
Gene ID number: 9846
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: CrkL and SHC, Gab2 acts as a docking protein for several SH2-containing proteins, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, Gab2 is a substrate of various RTKs, Upon tyrosine phosphorylation, cytokine receptors as well as B and T cell antigen receptors, growth factors and cytokines, including EGFR, insulin receptor, Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs)
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 675nm/694nm
Synonyms: KIAA0571
Properties: Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target: GAB2 (Tyr643) Conjugated
Short name: Conjugated, GAB2 (Tyr643) Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: 5, Cy5
Alternative name: cyanine 5, 5 coupled, GRB2-associated binding protein 2 (Tyr643) (Antibody to)
Alternative technique: antibodies
Alternative to gene target: GAB2 and IDBG-65975 and ENSG00000033327 and 9846, Plasma membranes, phosphatidylinositol-3, this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0005547 : phosphatidylinositol-3, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005515 : protein binding, this GO :0005547 : phosphatidylinositol-3, this GO :0043325 : phosphatidylinositol-3, 4, 4, 4, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0043325 : phosphatidylinositol-3, 5-trisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0043325 and phosphatidylinositol-3, GRB2-associated binding protein 2
Identity: 14458
Gene: GAB2 | More about : GAB2
Long gene name: GRB2 associated binding protein 2
Synonyms name: Grb2-associated binder 2
Locus: 11q14, 1
Discovery year: 2001-01-24
GenBank acession: AB011143
Entrez gene record: 9846
Pubmed identfication: 10391903 10068651
RefSeq identity: NM_080491
Classification: Pleckstrin homology domain containing
Havana BLAST/BLAT: OTTHUMG00000166673

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