| Long name: |
FAK (Tyr397) Primary Polyclonal Antibody |
| Also known as: |
FAK (Tyr397) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FAK Tyr397 |
| Specificity: |
This phosphorylation site is homologous to that of Tyr428 in Mouse and Tyr397 in Rat, This is a highly specific antibody against FAK Tyr397 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr397 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
352-402/1052 |
| Subcellular location: |
Cell membrane, Nucleus, Cytoplasm |
| Source: |
KLH cunjugated synthetic phosphopeptide derived from human FAK 1 around the phosphorylation site of Tyr397 |
| Gene ID number: |
5747 |
| Swiss Prot: |
Q05397 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix, Dec 2010], Several transcript variants encoding different isoforms have been found for this gene, The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies, [provided by RefSeq, but the full-length natures of only three of them have been determined, This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FADK, FADK 1, FAK1, FRNK, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, PPP1R71, PTK2, Protein phosphatase 1 regulatory subunit 71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, FAK |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FAK (Tyr397) |
| Short name: |
FAK (Tyr397) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FAK (Tyr397) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9611 |
| Gene: |
PTK2 |
More about : PTK2 |
| Long gene name: |
protein tyrosine kinase 2 |
| Synonyms gene name: |
PTK2 protein tyrosine kinase 2 |
| Synonyms: |
FAK FADK FAK1 PPP1R71 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 71 |
| Locus: |
8q24, 3 |
| Discovery year: |
1992-10-02 |
| GenBank acession: |
L13616 |
| Entrez gene record: |
5747 |
| Pubmed identfication: |
8422239 |
| RefSeq identity: |
NM_005607 |
| Classification: |
Protein phosphatase 1 regulatory subunits FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000067438 |