| Long name: |
Cy3 Conjugated, c-Fos (Ser32) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
c-Fos Ser32 |
| Specificity: |
This is a highly specific antibody against c-Fos Ser32 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser32 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
10-60/380 |
| Subcellular location: |
Intracellular |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Ser32 |
| Gene ID number: |
2353 |
| Swiss Prot: |
P01100 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites, Has a critical function in regulating the development of cells destined to form and maintain the skeleton, In growing cells, In the heterodimer, It is thought to have an important role in signal transduction, On TGF-beta activation, This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum, activates phospholipid synthesis, cell proliferation and differentiation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling, possibly by activating CDS1 and PI4K2A, Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
AP-1, C-FOS, Cellular oncogene fos, FOS, G0/G1 switch regulatory protein 7, G0S7, Proto-oncogene c-Fos, p55 |
| Properties: |
1 of the c-Fos (Ser32) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
c-Fos (Ser32) Conjugated |
| Short name: |
Conjugated, c-Fos (Ser32) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, c-FBJ murine osteosarcoma viral oncogene homolog (Ser32) (Antibody to) |
| Alternative technique: |
antibodies |