| Also known as: |
FOS / c-FOS |
| Other names: |
Cellular oncogene fos, FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS), FBJ murine osteosarcoma viral oncogene homolog, G0/G1 switch regulatory protein 7, G0/G1 switch regulatory protein 7, Proto-oncogene c-Fos, activator protein 1, cellular oncogene c-fos, proto-oncogene c-Fos, proto-oncogene c-Fos |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
FOS |
| Gene name synonims: |
c-FOS |
| Other gene names: |
AP-1, C-FOS, FOS, G0S7, p55, FOS |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
1H8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human FOS / c-FOS |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Concentration: |
2 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 1H8] (IgG2a, k) FOS / c-FOS |
| Short name: |
Mouse Monoclonal [clone 1H8] (IgG2a, k) FOS / c-FOS Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens FBJ murine osteosarcoma viral oncogene homolog / c-FBJ murine osteosarcoma viral oncogene homolog (Antibody to), Mouse monoclonal [clonality 1H8] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AP-1 and C-FOS and p55, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006954 and inflammatory response and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007565 and female pregnancy and biological process this GO :0007568 and aging and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0009409 and response to cold and biological process this GO :0009416 and response to light stimulus and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009629 and response to gravity and biological process this GO :0009636 and response to toxic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0030431 and sleep and biological process this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032570 and response to progesterone and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0034614 and cellular response to reactive oxygen species and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035902 and response to immobilization stress and biological process this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0043005 and neuron projection and cellular component this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045672 and positive regulation of osteoclast differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051412 and response to corticosterone and biological process this GO :0051591 and response to cAMP and biological process this GO :0060395 and SMAD protein signal transduction and biological process this GO :0070412 and R-SMAD binding and molecular function this GO :0071277 and cellular response to calcium ion and biological process, FOS and IDBG-12957 and ENSG00000170345 and 2353, FOS and IDBG-646869 and ENSBTAG00000004322 and 280795, Fos and IDBG-158538 and ENSMUSG00000021250 and 14281, R-SMAD binding, nuclei, this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001661 and conditioned taste aversion and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006306 and DNA methylation and biological process this GO :0006355 and regulation of transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003677 : DNA binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0070412 : R-SMAD binding, this GO :0003677 : DNA binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0070412 : R-SMAD binding, FBJ murine osteosarcoma viral oncogene homolog |
| Identity: |
3796 |
| Gene: |
FOS |
More about : FOS |
| Long gene name: |
AP-1 transcription factor subunit , Fos proto-oncogene |
| Synonyms gene name: |
v-fos FBJ murine osteosarcoma viral oncogene homolog FBJ murine osteosarcoma viral oncogene homolog |
| Synonyms: |
c-fos AP-1 |
| Locus: |
14q24, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
K00650 |
| Entrez gene record: |
2353 |
| Pubmed identfication: |
16123044 16055710 15926923 |
| RefSeq identity: |
NM_005252 |
| Classification: |
Fos transcription factor family Basic leucine zipper proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000171774 |