| Catalog number: | bs-3138R |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | FoxO3a (Ser318 + Ser321) Antibody |
| Quantity: | 100ul |
| Related search: |
| Long name: | FoxO3a (Ser318 + Ser321) Antibody |
|---|---|
| Also known as: | FoxO3a (Ser318 + Ser321) Antibody |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | FoxO3a Ser318 + Ser321 |
| Specificity: | Due to the highly conserved nature of this sequence, Ser319 and Ser322 in Mouse, These phosphorylation sites are homologous to Ser317 + Ser320 in Mouse and Rat, and Ser316 and Ser319 in Rat, there is a chance that this antibody will react with FoxO1a when phosphorylated at the the sites of Ser322 and Ser325 in Human, This is a highly specific antibody against FoxO3a Ser318 + Ser321 |
| Modification(s): | Phosphorylation |
| Modification site(s): | Ser318 + Ser321 |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 290-340/673 |
| Subcellular location: | Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser318/321 |
| Gene ID number: | 2309 |
| Swiss Prot: | O43524 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation, Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3', including neuronal cell death upon oxidative stress, promotes induction of miR-34b and miR-34c expression, Transcriptional activator which triggers apoptosis in the absence of survival factors |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | AF6q21, AF6q21 protein, FKHRL1, FKHRL1P2, FOXO3, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1, FOXO2 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | FoxO3a (Ser318 + Ser321) |
| Short name: | FoxO3a (Ser318 + Ser321) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | FoxO3a (Ser318 and Ser321) (Antibody to) |
| Alternative technique: | antibodies |
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