Dab1 (Tyr220) Antibody

Catalog number:	bs-3114R Buy Now
Price:	688 €
Supplier:	acr
Product name:	Dab1 (Tyr220) Antibody
Quantity:	0,2 ml
Related search:	dab antibody antibodies disabled gene homolog yotari

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Long name:	Dab1 (Tyr220) Primary Polyclonal Antibody
Also known as:	Dab1 (Tyr220) PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Dab1 Tyr220
Specificity:	This is a highly specific antibody against Dab1 Tyr220
Modification(s):	Phosphorylation
Modification site(s):	Tyr220
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Tyr220
Gene ID number:	1600
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Dab1 also mediates activation of Akt (PKB) by reelin resulting in inhibition of glycogen synthase kinase 3 beta (GSK-3 beta) and decreased phosphorylation of the microtubule-associated protein, Dab1 contains a phosphotyrosine binding (PTB) domain in the amino terminus, Dab1 is an intracellular adapter protein that functions in downstream signaling events initiated by the secreted protein reelin, Dab1 serine 491 is phosphorylated in a Cdk5-dependent manner and regulates, Phenotypically, Reelin-induced signaling during neural cortex development, Src family kinase and c-Abl activities are themselves then stimulated by binding to tyrosine phosphorylated Dab1, Tau, Tyrosine phosphorylation of Dab1 is increased by reelin binding to the Very Low Density Lipoprotein Receptor (VLDLR) and Apolipoprotein E Receptor 2 (ApoER2) through stimulation of Src family kinases, and severe cerebellar hypoplasia, disruption of neuronal migration, likely indirectly, the mutation of this gene produces motor defects and ataxia, Disabled 1 (Dab1) is an 80 kDa protein that is encoded by the Disabled-1 gene locus which is mutated in scrambler and yotari mutant mice
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari, Dab 1
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Dab1 (Tyr220)
Short name:	Dab1 (Tyr220) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	disabled homolog 1 (Drosophila) (Tyr220) (Antibody to)
Alternative technique:	antibodies

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