| Long name: |
ALEXA FLUOR 350 Conjugated, Bcl-2 (Thr56) Polyclonal Antibody |
| Also known as: |
Anti-Bcl-2 Thr56 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Bcl-2 Thr56 |
| Specificity: |
This is a highly specific antibody against Bcl-2 Thr56 |
| Modification: |
Phosphorylation |
| Modification Site: |
Thr56 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Bcl-2 around the phosphorylation site of Thr56 |
| Gene ID Number: |
596 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also interacts with APAF1, BAD, BAK and BclX(L), BBC3, BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1), BCL2L1 and BNIPL, Constitutive expression of BCL2, Heterodimerization with BAX requires intact BH1 and BH2 domains, It appears to function in a feedback loop system with caspases, It can form homodimers, It regulates cell death by controlling the mitochondrial membrane permeability, RAF1, TP53BP2, Two transcript variants (alpha and beta) produced by alternate splicing, and heterodimers with BAX, and is necessary for anti-apoptotic activity, differ in their C-terminal ends, is thought to be the cause of follicular lymphoma, such as in the case of translocation of BCL2 to Ig heavy chain locus, BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes, BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
2, AW986256, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl2, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, B-cell, BCL2 protein, BCL2_HUMAN, Bcl 2, Bcl-2, Bcl2, Bcl2 phospho Thr56, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, Oncogene B-cell leukemia 2, p-Bcl2 phospho T56, Bcl2 phospho T56 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Bcl-2 (Thr56) |
| Short name: |
Bcl-2 (Thr56) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Bcl-2 (Thr56) (Antibody to) |
| Alternative technique: |
antibodies |