| Long name: |
14-3-3 protein zeta/delta (S58) Antibody |
| Also known as: |
14-3-3 protein zeta/delta (S58) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
14-3-3 protein zeta/delta Ser58 |
| Specificity: |
This antibody will react with all 14-3-3 proteins containing the conserved motif RS(S-p)WR, This is a highly specific antibody against 14-3-3 protein zeta/delta Ser58 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser58 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
30-70/245 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human 14-3-3 protein zeta/delta around the phosphorylation site of Ser58 [RS(p-S)WR] |
| Gene ID number: |
7529, 7534, 10971 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases, Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions, They are also present, and are axonally transported to the nerve terminals, at lower levels, in various other eukaryotic tissues, including those involved in cell cycle regulation and cell survival, localized in neurons, Members of the 14-3-3 family of proteins are highly conserved proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
14 3 3, 14 3 3 protein beta, 14 3 3 protein beta/alpha, 14 3 3 protein zeta, 14-3-3 protein beta/alpha, 1433Z_HUMAN, Full=14-3-3 protein zeta/delta, GW128, HS1, KCIP 1, KCIP-1, KCIP-1, Protein 1054, Protein kinase C inhibitor protein 1, Protein kinase C inhibitor protein 1, YWHAA, YWHAB, YWHAE, YWHAZ, YWHAZphospho S58, YWHAEphospho S58 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
14-3-3 protein zeta/delta (S58) |
| Short name: |
14-3-3 protein zeta/delta (S58) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
14-3-3 protein zeta/delta (S58) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12854 |
| Gene: |
YWHAQ |
More about : YWHAQ |
| Long gene name: |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| Synonyms gene name: |
theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Synonyms: |
HS1 14-3-3 |
| Synonyms name: |
protein tau |
| Locus: |
2p25, 1 |
| Discovery year: |
1999-08-20 |
| GenBank acession: |
AF070556 |
| Entrez gene record: |
10971 |
| Pubmed identfication: |
11080204 |
| RefSeq identity: |
NM_006826 |
| Classification: |
14-3-3 phospho-serine/phospho-threonine binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000013848 |