| Long name: |
HRP Conjugated, Mitofusin 2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Mitofusin 2 |
| Specificity: |
This is a highly specific antibody against Mitofusin 2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1-50/757 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human Mitofusin 2 |
| Gene ID number: |
9927 |
| Swiss Prot: |
O95140 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions, Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy), Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress, Is required for PARK2 recruitment to dysfunctional mitochondria, It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes, MFN2 acts independently of the cytoskeleton, Overexpression induces the formation of mitochondrial networks, Plays an important role in the regulation of vascular smooth muscle cell proliferation, which is balanced between fusion and fission, which mediates mitochondrial fusion, Essential transmembrane GTPase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CMT2A, CMT2A2, CPRP1, KIAA0214, MARF, MFN2, Mitofusin-2, Transmembrane GTPase MFN2, HSG |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
Mitofusin 2 Conjugated |
| Short name: |
Conjugated, Mitofusin 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, Mitofusin 2 (Antibody to) |
| Alternative technique: |
antibodies |