| Long name: |
Biotin Conjugated, GGT1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GGT1 |
| Specificity: |
This is a highly specific antibody against GGT1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
380-430/569 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GGT1 |
| Gene ID number: |
2678 |
| Swiss Prot: |
P19440 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In the presence of high concentrations of dipeptides and some amino acids, Initiates extracellular glutathione (GSH) breakdown, Isoform 3 seems to be inactive, It is part of the cell antioxidant defense mechanism, The metabolism of glutathione releases free glutamate and the dipeptide, and other gamma-glutamyl compounds, can also catalyze a transpeptidation reaction, cysteinyl-glycine, glutathione conjugates, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound, which is hydrolyzed to cysteine and glycine by dipeptidases, Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
D22S672 D22S732 CD224 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GGT1 Conjugated |
| Short name: |
Conjugated, GGT1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GGT1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4250 |
| Gene: |
GGT1 |
More about : GGT1 |
| Long gene name: |
gamma-glutamyltransferase 1 |
| Synonyms gene: |
GGT |
| Locus: |
22q11, 23 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M24903 |
| Entrez gene record: |
2678 |
| Pubmed identfication: |
8104871 18357469 |
| RefSeq identity: |
NM_013430 |
| Classification: |
Gamma-glutamyltransferases CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000030859 |